Hi this is my first time posting in an image board like this, forgive me if this is shit.
I think that maybe, maybe, Madotsuki's life was sheltered. Surely if she started out normal to begin with she would know full well that there are plenty of men and women. However, we only see girls apart from a dead man and Masada-sensei.
I was thinking that she could actually be a rich girl with a father that was too busy working and a mother who was pregnant when she hid herself away. The mother also would not have time for her, for the mother was too busy gossiping and being a trophy wife with other trophy wives.
Insert Madotsuki, who was practically raised to be a hikikomori, having all she ever wanted if she just asked of it. However, the lack of social interaction as a child meant she felt comfort in being alone with things that entertained her for hours (NASU, and the lack of cable). Also explains how she can just not go to school and be fine.
Perhaps, the other girls were Mado's Mother's Friends' daughters. Feeling they would get together more, Poniko with her enjoyment for the macabre and the frightening used to frighted Mado with masks in the dark when they slept over at Poniko's house. As for the two girls (5 armed one and the other one, forgot names) they could possibly be sisters, one having gotten in an accident of some sort and mutilating her. The other one might've blamed Mado for this, that's why you gotta kill a man to see her.
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